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   1976| January-March  | Volume 22 | Issue 1  
    Online since September 10, 2008

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Inflammatory process and screening methods for anti-inflammatory agents- a review
SR Naik, UK Sheth
January-March 1976, 22(1):5-21
  21,580 0 -
Extra-amniotic mannitol for pregnancy termination - (preliminary report)
Malini A Deshmukh, Sushila Shah, S Shah, Shobha J Joglekar
January-March 1976, 22(1):23-25
To induce termination of pregnancy, during 11 to 20 , weeks' period of gestation, extra-amniotic 20% Mannitol solution was used, in 40 patients. The amount of Mannitol varied from 350 ml. to 1290 ml. over a period o f 24 to 48 hours, through a Foley's catheter. After the patient started aborting, Pitocin 2 units were given I.M., every half hourly for 4 injections. The success rate was 95%. Mean induction time for abortion was 33.8 hrs. No adverse effects were noted. This is only a preliminary report and further studies in progress will be reported later.
  3,710 0 -
Levodopa in the treatment of hepatic coma due to fulminant hepatic failure
JM Mehta, SG Karamarkar, BD Pimparkar, UK Sheth
January-March 1976, 22(1):32-36
Fifteen cases of -advancing stupor or coma due to viral hepa­titis, received levodopa intragastrically in the dose of 4 Gm. per day, in addition to the routine treatment of i.v. glucose, bowel wash -neomycin, parenteral corticosteroids and antibiotics. Liver Biopsy in all cases showed a massive liver cell necrosis. 4 patients regain­ed consciousness. 2 of these cases recovered and two others died on 15th day after starting the treatment. The rest of the patients died at different time intervals between 4th and 5th days. Although mortality in this series was high, levodopa had a definite and im­pressive awakening effect.
  3,558 0 -
Unusual presentation of acute myeloid leukemia
PD Anjaria, UG Gadgil, SM Gaikwad
January-March 1976, 22(1):44-46
A case of acute myeloid leukemia with unusual- presentation of compression paraplegia of acute onset, with extensive epidural plaque is reported. Mechanisms of neurologic manifestations, espe­cially involvement of the spinal cord, of leukemia, are discussed.
  2,198 0 -
A preliminary study of etafenoxine
DR Doongaji, AS Sheth, JS Apte, MPE Bharucha, SP Ramesh, KN Padamsee, VN Vahia
January-March 1976, 22(1):37-43
Etafenoxine (Hoe 36 801), a new psychotropic compound was administered in a single blind study to 16 neurotic outpatients and 15 schizophrenic inpatients for a period of 4 weeks followed by a 2 week period of placebo administration. Improvement was report­ed for the psychic and somatic symptoms of anxiety accompanied by depression. The improvement observed in psychotic symptoms was minimal. Negligible side effects were noted in 6 patients.
  2,173 0 -
The nephrotic syndrome (a follow up study of 32 cases)
Mahrukh K Joshi, Pravina W Kandoth, Suman M Sant, MP Bhagat
January-March 1976, 22(1):26-31
32 cases of nephrotic syndrome treated with steroids and fol­lowed up for upto 8 years have been analysed. The series con­sisted of 17 boys and 15 girls. Nineteen cases had an onset of the disease below 6 years of age, the rest after this age. Biochemical studies were done in all cases, and renal biopsies were performed in 18 cases and repeated in 2 cases. Minimal changes were present in 3 cases and structural changes in 15 cases. Three patients were declared cured, 17 were declared to be in remission, 8 were relaps­ing and 4 expired. The correlation of age at onset, sex, biochemical findings, histopathologic findings and time of relapse with the final outcome has been discussed. Prognosis was better in boys and in cases having onset of the disease after 6 years of age. Hypertension and hematuria were associated with structural changes in biopsy. Absence of relapses or their cessation after the first two years of the disease signified a good prognosis.
  2,112 0 -
Role of medical institutions in the development of new drugs
UK Sheth
January-March 1976, 22(1):1-4
  1,882 0 -
Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow