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Levetiracetam-induced gingival hyperplasia
J James, J Jose, VA Gafoor
Department of Neurology, Government Medical College, Kozhikode, Kerala, India
Correspondence Address:
J Jose
Department of Neurology, Government Medical College, Kozhikode, Kerala
India
Levetiracetam is a new generation antiseizure medication which binds to synaptic vesicle protein SV2A and inhibits the release of neurotransmitters. Gingival hyperplasia is a common side effect of conventional antiseizure medications like phenytoin, but very rare with the newer ones. A 14-year-old boy was started on levetiracetam 250 mg twice daily after a generalized seizure. Five days later he presented with gingival swelling and painful oral aphthae, without lymphadenopathy or systemic symptoms. Blood investigations were normal. After one-month of stopping the drug, the lesions cleared. This case highlights the importance of maintaining good oral hygiene and periodic dental review in patients on antiseizure medications.
How to cite this article:
James J, Jose J, Gafoor V A. Levetiracetam-induced gingival hyperplasia.J Postgrad Med 2022;68:168-169
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How to cite this URL:
James J, Jose J, Gafoor V A. Levetiracetam-induced gingival hyperplasia. J Postgrad Med [serial online] 2022 [cited 2023 Jun 1 ];68:168-169
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2022;volume=68;issue=3;spage=168;epage=169;aulast=James;type=0 |
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