Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & EMBASE  
     Home | Subscribe | Feedback  

TECHNOLOGY REVIEW
[View FULLTEXT] [Download PDF
 
Year : 2011  |  Volume : 57  |  Issue : 2  |  Page : 153-160  

Drug repositioning: Re-investigating existing drugs for new therapeutic indications

BM Padhy1, YK Gupta2 
1 Department of Pharmacology, Hamdard Institute of Medical Sciences and Research, New Delhi, India
2 Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
B M Padhy
Department of Pharmacology, Hamdard Institute of Medical Sciences and Research, New Delhi
India

Drug discovery and development is an expensive, time-consuming, and risky enterprise. In order to accelerate the drug development process with reduced risk of failure and relatively lower costs, pharmaceutical companies have adopted drug repositioning as an alternative. This strategy involves exploration of drugs that have already been approved for treatment of other diseases and/or whose targets have already been discovered. Various techniques including data mining, bioinformatics, and usage of novel screening platforms have been used for identification and screening of potential repositioning candidates. However, challenges in clinical trials and intellectual property issues may be encountered during the repositioning process. Nevertheless, such initiatives not only add value to the portfolio of pharmaceutical companies but also provide an opportunity for academia and government laboratories to develop new and innovative uses of existing drugs for infectious and neglected diseases, especially in emerging countries like India.


How to cite this article:
Padhy B M, Gupta Y K. Drug repositioning: Re-investigating existing drugs for new therapeutic indications.J Postgrad Med 2011;57:153-160


How to cite this URL:
Padhy B M, Gupta Y K. Drug repositioning: Re-investigating existing drugs for new therapeutic indications. J Postgrad Med [serial online] 2011 [cited 2022 Aug 15 ];57:153-160
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2011;volume=57;issue=2;spage=153;epage=160;aulast=Padhy;type=0


 
Monday, August 15, 2022
 Site Map | Home | Contact Us | Feedback | Copyright  and disclaimer