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Primary diffuse leptomeningeal primitive neuroectodermal tumor presenting as chronic meningitis
KG Koshy1, GB Kulkarni1, BN Nandeesh2, AV Taalapalli1
1 Department of Neurology, NIMHANS, Bangalore, Karnataka, India
2 Department of Neuropathology, NIMHANS, Bangalore, Karnataka, India
Correspondence Address:
GB Kulkarni,
Department of Neurology, NIMHANS, Bangalore, Karnataka
India
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/jpgm.jpgm_495_22 PMID: 36891942
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Primary diffuse leptomeningeal primitive neuroectodermal tumor is a rare meningeal neoplasm which can masquerade as chronic meningitis. While the clinical presentation and radiological features may provide a clue to this condition, meningeal biopsy is essential to clinch the diagnosis. A high index of suspicion and a low threshold for re-evaluating cases of neuroinfection that do not respond to empirical therapy are essential in this scenario. We present the case of a nine year old boy who was initiated on antituberculous treatment for chronic meningitis with hydrocephalus. Meningeal biopsy revealed a primary diffuse leptomeningeal primitive neuroectodermal tumor.
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