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Year : 2022  |  Volume : 68  |  Issue : 2  |  Page : 112-114

Sialadenoma papilliferum of a minor salivary gland with transformation to mucoepidermoid carcinoma

1 Department of Pathology, Deen Dayal Upadhayay Hospital, Hari Nagar, New Delhi, India
2 Division of Cytopathology, ICMR-National Institute of Cancer Prevention and Research, I-7, Noida, Uttar Pradesh, India

Correspondence Address:
S Gupta
Division of Cytopathology, ICMR-National Institute of Cancer Prevention and Research, I-7, Noida, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpgm.jpgm_912_21

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Sialadenoma papilliferum (SP) is a rare benign tumor usually occurring in the minor salivary glands. Only two cases of malignant transformation of SP and an occasional case of dysplasia in SP have been reported in the literature till now. We report a case of SP of a minor salivary gland in a middle-aged male where the exophytic component retained the histomorphological features of SP while the endophytic component displayed characteristics of a mucoepidermoid carcinoma. Malignant change in sialadenoma papilliferum is an extremely rare phenomenon that requires further research and documentation. Careful evaluation of morphologic features and reporting of more such cases is required to delineate the clinical behavior of this unusual tumor.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow