Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & ISI's SCI  
Users online: 752  
Home | Subscribe | Feedback | Login 
About Latest Articles Back-Issues Articlesmenu-bullet Search Instructions Online Submission Subscribe Etcetera Contact
 ::  Similar in PUBMED
 ::  Search Pubmed for
 ::  Search in Google Scholar for
 ::  Article in PDF (751 KB)
 ::  Citation Manager
 ::  Access Statistics
 ::  Reader Comments
 ::  Email Alert *
 ::  Add to My List *
* Registration required (free) 

  IN THIS Article
 ::  References
 ::  Article Figures

 Article Access Statistics
    PDF Downloaded17    
    Comments [Add]    
    Cited by others 3    

Recommend this journal


  Table of Contents     
Year : 2020  |  Volume : 66  |  Issue : 1  |  Page : 57-58

Intramedullary osteoid osteoma in an 11-month-old child

Department of Orthopaedics, Lady Hardinge Medical College, New Delhi, India

Date of Submission16-Jun-2019
Date of Acceptance14-Oct-2019
Date of Web Publication13-Jan-2020

Correspondence Address:
S Sinha
Department of Orthopaedics, Lady Hardinge Medical College, New Delhi
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpgm.JPGM_326_19

Rights and Permissions

How to cite this article:
Gupta S, Sinha S, Narang A, Kanojia R K. Intramedullary osteoid osteoma in an 11-month-old child. J Postgrad Med 2020;66:57-8

How to cite this URL:
Gupta S, Sinha S, Narang A, Kanojia R K. Intramedullary osteoid osteoma in an 11-month-old child. J Postgrad Med [serial online] 2020 [cited 2023 Sep 28];66:57-8. Available from:

We report an 11-month-old boy who presented with inconsolable crying, swelling, and decreased use of left lower limb since the age of 8 months. Child was apparently well until the age of 8 month when the parents noticed crying due to pain. Initially pain was intermittent and mild: however, it increased progressively in intensity and frequency. At the time of presentation pain was so severe that he had to be given analgesic at least twice to have a proper sleep. Apart from this problem his history was unremarkable since birth. Parent had sought treatment at nearby hospital where analgesics were given, but as the child did not improve radiographs followed by magnetic resonance imaging (MRI) of affected extremity weredone [Figure 1]a and [Figure 1]b. Despite extensive work-up the diagnosis was not clear and he was referred to our institute with differential diagnosis of osteomyelitis or Ewing tumor as per MRI report.
Figure 1: (a) Plain radiograph showing nidus surrounded by sclerosis. (b) MRI showing areas of hyperechogenicity. (c) CT scan showing intramedullary nidus

Click here to view

On examination, the child was well nourished and alert. There was a diffuse ill-defined swelling of 5 × 4 cm on the anteromedial aspect of left tibia which was bony hard and tender. Local temperature and overlying skin were normal. Affected leg circumference was increased by 1 cm; there was no limb length discrepancy, no signs of neurovascular compromise and no restriction of range of motion of affected joint.

As there was no sign of malignant disease on examination and there was a radiolucent shadow in radiograph, we did computed tomography (CT) scan of affected extremity to confirm the diagnosis of osteoid osteoma. CT scan of tibia confirmed our diagnosis [Figure 1]c. An excision biopsy of suspected nidus using an anteromedial approach to tibia was done. A bone window was made, nidus and surrounding bone was curetted and sent for histopathological examination [Figure 2]a. Diagnosis of osteoid osteoma was confirmed histopathologically [Figure 2]c. On 1-year follow-up the child was asymptomatic and radiographs revealed a healed bony window [Figure 2]b.
Figure 2: (a) Intraoperative pictures showing bone window. (b) Plain radiograph showing healed bone window. (c) Photomicrograph showing anastomosing bony trabeculae (broad arrow) rimmed by osteoblasts (thin arrow) (H and E, ×400)

Click here to view

Osteoid osteoma very rarely presents in less than 1 year of age. Restlessness, inability to sleep at night, decreased use of affected limb, and absence of kicking are reported presentation of osteoid osteoma in children.[1],[2],[3] Limb length discrepancy, wasting, deformity, and swelling are also common findings in a child suspected to having osteoid osteoma.[1],[4]

Three types of osteoid osteoma based on the radiographic localization of nidus have been described in literature: cortical (if nidus is within cortex), subperiosteal (if nidus is located outside the cortex, surrounded by periosteal reaction), and intramedullary (if nidus is located inside medullary cavity). Intramedullary (also known as cancellous) osteoid osteoma is relatively rare.

In our patient, nidus was located intramedullary, which was a diagnostic challenge because the typical radiographic finding of central lucent zone(nidus) and sclerosis of the surrounding bone tissue was minimal. CT scan is regarded as best investigation to locate nidus and confirm the diagnosis of osteoid osteoma. The tumor nidus may be difficult to identify on MRI. The presentation of intramedullary osteoid osteomas is often mistaken for Ewing's sarcoma.

CT-guided percutaneous radiofrequency thermal ablation is considered treatment of choice for osteoid osteoma. Its role for children and in intramedullary osteoid osteoma is still under evaluation.[5]

Complete surgical removal of nidus is preferred treatment in children to prevent bony deformity, limb length discrepancy, and recurrence.

Declaration of patient consent

The authors certify that appropriate patient consent was obtained.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

 :: References Top

Habermann ET, Stern RE. Osteoid-osteoma of the tibia in an eight-month-old boy: A case report. JBJS 1974;56:633-6.  Back to cited text no. 1
Laurence N, Epelman M, Markowitz RI, Jaimes C, Jaramillo D, Chauvin NA. Osteoid osteomas: A pain in the night diagnosis. Pediatr Radiol 2012;42:1490-501.  Back to cited text no. 2
Purcell HM, Mills SD, Lipscomb PR. Osteoid osteoma in childhood. Pediatrics 1952;9:295-303.  Back to cited text no. 3
Sherman MS. Osteoid osteoma: Review of the literature and report of thirty cases. JBJS 1947;29:918-30.  Back to cited text no. 4
Virayavanich W, Singh R, O'Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol 2010;39:1145-9.  Back to cited text no. 5


  [Figure 1], [Figure 2]

This article has been cited by
1 Benign Bone Tumors: An Overview of What We Know Today
Sara De Salvo, Vito Pavone, Sebastiano Coco, Eleonora Dell’Agli, Chiara Blatti, Gianluca Testa
Journal of Clinical Medicine. 2022; 11(3): 699
[Pubmed] | [DOI]
2 Intramedullary osteoid osteoma in the humerus of a toddler—A case report and review of the literature
Mizuki Hiramatsu, Robert Nakayama, Tomoki Kasahara, Rumi Nakagawa, Toru Hirozane, Sayaka Yamaguchi, Tomoaki Mori, Naofumi Asano, Hajime Okita, Masaya Nakamura, Morio Matsumoto
Radiology Case Reports. 2022; 17(10): 3748
[Pubmed] | [DOI]
3 CT-Guided Radiofrequency Thermal Ablation for the Treatment of Atypical, Early-Onset Osteoid Osteoma in Children Younger than 4 Years Old: Single-Institution Experience and Literature Review
Nicolas Papalexis, Giuliano Peta, Federico Ponti, Gianmarco Tuzzato, Marco Colangeli, Giancarlo Facchini, Paolo Spinnato
Diagnostics. 2022; 12(11): 2812
[Pubmed] | [DOI]


Print this article  Email this article
Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow