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| ADR REPORT |
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| Year : 2014 | Volume
: 60
| Issue : 2 | Page : 189-191 |
Cardiovascular abnormalities with single dose of tapentadol
A Vachhani1, M Barvaliya2, V Naik1, CB Tripathi1
1 Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, India
2 Department of Pharmacology, Gujarat Medical Education and Research Society Medical College, Patan, Gujarat, India
Correspondence Address:
Dr. C B Tripathi
Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0022-3859.132341
This case represents the development of dizziness, palpitation, tightness in chest, flushing, and tremor on consumption of a single dose of tapentadol (100 mg) for acute lower back pain. The patient was admitted in the intensive cardiac care unit for continuous monitoring. At admission, electrocardiogram showed tachycardia (140/min) along with ST segment elevation in second chest lead (V 2 ). The patient was monitored and advised not to take further doses of tapentadol. He was discharged after 36 hours of admission. Tapentadol should be used cautiously in patients with cardiovascular diseases and receiving sympathomimetic drugs.
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