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| TECHNOLOGY REVIEW |
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| Year : 2008 | Volume
: 54
| Issue : 2 | Page : 158-162 |
Tissue microarray: A simple technology that has revolutionized research in pathology
S Avninder1, K Ylaya2, SM Hewitt2
1 Institute of Pathology-ICMR, New Delhi, India
2 Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, USA
Correspondence Address:
S Avninder
Institute of Pathology-ICMR, New Delhi
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0022-3859.40790
Tissue microarray (TMA) technology is a high-throughput research tool, which has greatly facilitated and accelerated tissue analyses by in-situ technologies. TMAs are amenable to every research method that can be applied on the standard whole sections at enhanced speed. It plays a central role in target verification of results from cDNA arrays, expression profiling of tumors and tissues, and is proving to be a powerful platform for proteomic research. In this review article, primarily meant for students of pathology and oncology, we briefly discuss its basic methodology, applications and merits and limitations.
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