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| BRIEF REPORT |
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| Year : 2002 | Volume
: 48
| Issue : 2 | Page : 117-8 |
Clinical profile of leptospirosis in South gujarat.
AM Clerke, AC Leuva, C Joshi, SV Trivedi
Department of Medicine, Government Medical College, Surat - 395 001, Gujarat, India., India
Correspondence Address:
A M Clerke
Department of Medicine, Government Medical College, Surat - 395 001, Gujarat, India.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 12215693 
BACKGROUND: South Gujarat has been witnessing increasing incidence of leptospirosis for the last few years. AIM: To study the clinical profile of leptospirosis in South Gujarat. SETTINGS AND DESIGN: Prospective study during July-September 2000 at the New Civil Hospital, Surat, Gujarat. PATIENTS AND METHODS: All the consecutive cases with clinical suspicion of leptospirosis were screened for lgM antileptospira antibody on the first and the fourteenth day. A four fold or greater increase in agglutinin antibody titre on paired samples was considered diagnostic. If the patient died before the fourteenth day then initial titre greater than 1:15 was considered diagnostic. RESULTS: Total number of patients referred to the hospital were fifty, of which thirty-eight [33 males, with age 14-50 (30 +/- 10.51)] were diagnosed as having leptospirosis. Most common organs involved were liver (27, 71.05%) and kidney (24, 63.15%). Cardio-vascular (12, 31.5%), pulmonary (10, 26.35%), neurological (2, 5.26%) and haematological (8, 21%) involvements were less common. Six patients died because of pulmonary involvement in the form of alveolar haemorrhage, while one died because of cardiac involvement. CONCLUSION: Liver and kidney were the most commonly involved organs in severe leptospirosis. Pulmonary involvement, though uncommon, led to high mortality.
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