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| UPDATE ARTICLE |
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| Year : 2002 | Volume
: 48
| Issue : 1 | Page : 56-63 |
Allograft biopsies in management of pancreas transplant recipients.
P Randhawa
Division of Transplantation Pathology, Department of Pathology, C903.1 Presbyterian University Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA. , USA
Correspondence Address:
P Randhawa
Division of Transplantation Pathology, Department of Pathology, C903.1 Presbyterian University Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA.
USA
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 12082334 
Pancreatic transplantation is becoming increasingly accepted as a treatment modality for Type 1 diabetes mellitus. When allograft dysfunction is noted during follow up of patients, a biopsy is an extremely useful tool to diagnose various forms of rejection, and to rule out non-immunologic causes of graft malfunction, such as donor disease, ischaemic/preservation injury, vascular thrombosis, pancreatitis, post-transplant lymphoproliferative disease, technical complications and recurrence of diabetes mellitus. In addition to its role in establishing the primary diagnosis, a biopsy can grade the severity of pathology present, help determine the most appropriate therapy, and provide information relevant to graft prognosis.
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