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| CASE REPORT |
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| Year : 2000 | Volume
: 46
| Issue : 4 | Page : 278-9 |
Cerebellar atrophy in an epileptic child: is it due to phenytoin?
SR Ahuja, S Karande, MV Kulkarni
Division of Paediatric Neurology, Department of Paediatrics, LTM Medical College and Hospital, Sion, Mumbai - 400 022, India., India
Correspondence Address:
S R Ahuja
Division of Paediatric Neurology, Department of Paediatrics, LTM Medical College and Hospital, Sion, Mumbai - 400 022, India.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 11435657 
A four and half year old epileptic child on phenytoin therapy since one year presented with signs of cerebellar dysfunction. Serum phenytoin level was high (33 mcg/ml) and computerised tomographic scan of the brain showed severe generalised cerebellar atrophy. The cerebellar signs represented drug over dosage and toxicity and persisted long after omission of phenytoin.
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