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Year : 1995  |  Volume : 41  |  Issue : 4  |  Page : 95-8

The impact of cisplat based chemotherapy on advanced ovarian cancer.

Gynecologic Oncology Service, Tata Memorial Hospital, Parel, Bombay.

Correspondence Address:
G R Prasad
Gynecologic Oncology Service, Tata Memorial Hospital, Parel, Bombay.

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Source of Support: None, Conflict of Interest: None

PMID: 0010707728

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Cisplatinum based chemotherapy has become the standard treatment for ovarian cancers due to its proved superiority over non-cisplat based regimes. However, the therapeutic impact of cisplat based regimes compared to cheaper non-cisplatinum based regimes is questionable when multiple variables such as residual disease, histologic type, grade are introduced. This report is a study of 110 Stage III ovarian cancer patients from 1985-89, with cisplat (n = 69) and non cisplat (n = 41) based chemotherapy. The results of both regimes with reference to the multiple variable factors are presented. We conclude that cisplat based regimes appear to be superior to non-cisplat based regimes except probably in poorly differentiated ovarian tumors where the results were similar with either regimen.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow