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CASE REPORTS |
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Year : 1993 | Volume
: 39
| Issue : 3 | Page : 157-9 |
Myoglobinuria following the use of succinylcholine.
CG Bhave, KC Gadre, BS Gharpure
Correspondence Address:
C G Bhave
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 0008051650 
Eight hours following tympanoplasty performed under general anaesthesia (sodium pentothal and trichloroethylene), a 30 year old male complained of muscular weakness and dark coloured urine. Urinalysis revealed myoglobin pigment. A rise in BUN (47mg%), serum creatinine (5.7mg%), creatinine phosphokinase (15,500 U/L) and CPK-MB fraction (4690 U/L) was noticed 36 hrs later. The patient developed acute renal failure, and recovered after haemodialysis. From a history of use of succinylcholine as a muscle relaxant during operation, myoglobinuria appears to be secondary to muscle damage caused by succinylcholine.
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