Journal of Postgraduate Medicine
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Year : 1990  |  Volume : 36  |  Issue : 3  |  Page : 119-23

Correlation of serum vitamin A and its transport protein (RBP) in malnourished and vitamin A deficient children.

Dept. of Paediatrics, K. E. M. Hospital, Parel, Bombay, Maharashtra.

Correspondence Address:
M K Jain
Dept. of Paediatrics, K. E. M. Hospital, Parel, Bombay, Maharashtra.

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Source of Support: None, Conflict of Interest: None

PMID: 0002102908

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Eighty nine children were studied for retinol (vitamin A) estimation and its transport protein--retinol-Binding Protein (RBP). Serum levels of retinol, RBP and serum protein and albumin were found to be low in children with signs of vit. A deficiency irrespective of their nutritional status. Serum levels of retinol and RBP were risen significantly almost double, after the oral and parenteral administration of vitamin A. PEM interferes with hepatic synthesis of RBP and the release of RBP from the liver depends on vitamin A. Vitamin A is a limiting factor, the presence of which is required for the release of apo-RBP from the liver.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow