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| ORIGINAL ARTICLE |
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| Year : 1990 | Volume
: 36
| Issue : 1 | Page : 23-6 |
Paroxysmal nocturnal hemoglobinuria: a study of 17 cases.
RB Parab
Department of Hematology, Seth G. S. M. C., Parel, Bombay, Maharashtra.
Correspondence Address:
R B Parab
Department of Hematology, Seth G. S. M. C., Parel, Bombay, Maharashtra.
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 0002097351 
Retrospective analysis of 17 cases of paroxysmal nocturnal hemoglobinuria (PNH) was carried out. The presenting feature of anaemia and hemoglobin of less than 9 gm% were observed in all cases. Fever, jaundice and bleeding tendency were observed in 8, 8 and 7 cases respectively. Bone marrow examination revealed megaloblastic features, erythroid hyperplasia and hypocellularity in 8, 7 and 2 cases respectively. Fourteen cases were refractory to the treatment, while only 3 showed response.
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