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Year : 1990  |  Volume : 36  |  Issue : 1  |  Page : 23-6

Paroxysmal nocturnal hemoglobinuria: a study of 17 cases.

Department of Hematology, Seth G. S. M. C., Parel, Bombay, Maharashtra.

Correspondence Address:
R B Parab
Department of Hematology, Seth G. S. M. C., Parel, Bombay, Maharashtra.

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Source of Support: None, Conflict of Interest: None

PMID: 0002097351

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Retrospective analysis of 17 cases of paroxysmal nocturnal hemoglobinuria (PNH) was carried out. The presenting feature of anaemia and hemoglobin of less than 9 gm% were observed in all cases. Fever, jaundice and bleeding tendency were observed in 8, 8 and 7 cases respectively. Bone marrow examination revealed megaloblastic features, erythroid hyperplasia and hypocellularity in 8, 7 and 2 cases respectively. Fourteen cases were refractory to the treatment, while only 3 showed response.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow