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 ::  Introduction
 ::  Material And Methods
 ::  Results
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Year : 1979  |  Volume : 25  |  Issue : 4  |  Page : 197-200

Normal left atrial dimensions in indians by echo­cardiography

Department of Cardiology, K.E.M.Hospital, Parel, Bombay-400012, India

Correspondence Address:
D R Kulkarni
Department of Cardiology, K.E.M.Hospital, Parel, Bombay-400012
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Source of Support: None, Conflict of Interest: None

PMID: 529177

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 :: Abstract 

One hundred normal Indian subjects were studied to establish the normal left atrial dimension (LAD), left atrial dimension cor­rected to body surface area (LA index) and left atrium to aorta ratio (LA/AO) for this population. Normal mean LAD was 21.9 ± 3.6 mm (12 mm to 30 mm). Elderly subjects had higher mean LAD (25.2 ± 3.6 mm). The LA index for adults was 14.1 ± 2.5 mm. LA index for younger subjects was higher because of low body sur­face area. Mean LA/AO was 0.95± 0.22;LA/AO greater than 1.17 is suggested as a criterion for LA enlargement.

How to cite this article:
Kulkarni D R, Vengsarkar A S. Normal left atrial dimensions in indians by echo­cardiography. J Postgrad Med 1979;25:197-200

How to cite this URL:
Kulkarni D R, Vengsarkar A S. Normal left atrial dimensions in indians by echo­cardiography. J Postgrad Med [serial online] 1979 [cited 2023 Mar 26];25:197-200. Available from:

 :: Introduction Top

The left atrium is involved in an im­portant manner in the various diseases of mitral valve apparatus, [2] so commonly seen in India. The left atrial dimension therefore has a diagnostic and prognostic significance in clinical cardiology.

Echocardiographically one can measure the left atrial dimensions in both antero­posterior and supero-inferior diameters by parasternal and suprasternal approach respectively. [4] As the left atrium enlarges equally in all diameters [9] any one dia­meter is a reliable reflection of left atrial enlargement. Various studies have shown good correlation between the left atrial size i.e. diameter, measured by echocardiography and angiography. [8],[10]

As the left atrial dimension has a wide normal range, it has been correlated to the body surface area in an attempt to increase the clinical utility. The ratio of left atrial dimension to the aortic dimen­sion has also been devised for a more accurate assessment of left atrial size. [1]

All the values of normal and abnormal left atrial dimensions are established in the western population [1],[5],[7],[8],[9] These values are invalid for the Indian popula­tion on account of the lower body surface area related to the racial differences. So many of our enlarged left atria echo­cardiographically fall within the western normal limits. It is the object of this study to establish normal range of the left atrial dimension for Indian popula­tion. To our knowledge there are no reports on this subject in the literature.

 :: Material And Methods Top

One hundred normal subjects were studied. The age range was from 10 to 50 years; this appeared to match with the age of diseased population in so far as rheuma­tic heart disease is concerned. There were 8 five-year subgroups with a mini­mum of 10 patients in each subgroup. These subjects were examined thoroughly to rule out any disease likely to bear upon the heart directly or indirectly. The echoes were recorded with a Unirad sonograph machine. A non focused 2.25 mHz transducer of 13 mm diameter was used. The subjects were examined for mitral valve and left atrial echoes by methods routinely employed . [4] The left atrium was recorded at the level of aortic cusps; time gain compensation was used to yield optimum aortic wall echoes. These were recorded on a Honeywell strip chart recorder No. 1858. The left atrium was measured from the posterior edge of the posterior aortic wall to the anterior surface of the posterior left atrial wall at the end systole. The aorta was measured from the anterior surface of anterior wall to the anterior surface of posterior aortic wall at the end dias­tole [2] (See [Figure 1] on page 200 A). The height and weight were recorded in each patient and body surface area was calcu­lated from the nomogram by Dubois [3] The various values calculated were (i) Left atrial dimension, (ii) Ratio of left atrial diamension to the aortic dimension and (iii) Left atrial index i.e. left atrial dimension/body surface area (sq. meters). The dimensions were measured in millimetres for absolute values but the mean values are expressed upto one decimal point because of statistical averaging.

 :: Results Top

The mean left atrial dimension of all the patients was (21.9 ± 3.6 mm) [Table 1]. Statistically there was no significant difference between the mean values of the first 7 subgroups (19.8 ± 3.6 mm to 22.5 ± 4.7 mm). But the last subgroup (46 years to 50 years) had a mean value (25.2 ± 3.6 mm) which was just signi­ficantly higher than 4 of the 7 subgroups.

The mean LA/AO ratio for all patients was (0.95 ± 0.22). There was no signi­ficant difference between the mean values of the subgroup.

The mean LA index of all patients was (15.0 ± 2.5 mm). The mean LA index for the first subgroup was significantly higher (21.2 ± 2.9 mm) than the remain­ing (12.6 ± 2.5 mm to 15.8 ± 3.2 mm).

 :: Discussion Top

The left atrium is involved in various left heart diseases [2] and in some left to right shunts e.g. Patent Ductus Arterio­sus. [6] The measurement of left atrial dimension by echocardiography has an advantage over the angiographic mea­surements as the latter is an invasive procedure. [8]

The mean left atrial dimension in this study was 21.9 ± 3.6 mm. There was no significant difference between the mean value of younger subjects (21.3 ± 2.5 mm for 11 to 15 years and 19.8 ± 3.6 mm for 16 to 20 years subgroups); the mean value of the subgroup of 45 to 50 years had just significantly higher value (25.2 - 3.6 mm) which cannot be ex­plained satisfactorily. Other reported normal mean values of LAD are Hirata et al [8] - 3.1 ± 0.5 cm (1.8 to 4 cm), Brown et al [1] -3.23 cm (2.3 to 4.4 cm), and Francis et al [5]

28.5 - 5.1 mm (16 to 40 mm). These values are obviously higher than those reported in the present study.

The clinical utility of these normal values is blighted by a large overlap between the normal and abnormal left atrial dimensions. The large scatter of normal LAD is thought to be the result of difference in the body surface area. Hirata et al [8] and Brown et al [1] have re­ported that LA index is significantly cor­related to the body surface area whsle Hagan et al [7] and Francis et at [5] have reported to the contrary. In the present study no significant correlation was established. The mean LA index in the study was 15 ± 0.25 mm (9 mm to 21 mm). This was significantly higher in younger subjects of the 1st subgroup (21.2 ± 2.9 mm for 11 to 15 years). This was due to low body surface area with nor­mal LAD. The adult LA index was 14.1 -±2.5mm (12.6± 2.5 mm to 15.6 ± 3.2 mm). Normal LA index in the study of Hirata et al [8] is 1 to 2 cm/m [2] while in Brown's [1] study it is 1.2 to 2 cm/m [2] . These values are identical with the values in this series.

As LAD and LA index have a signi­ficant overlap between normal and enlar­ged left atria, another index (LA/AO) is contemplated to be more specific and reliable for LA enlargement. Brown et al [1] has reported that LA/AO ratio as a measure of LA enlargement is much more sensitive than LAD or LA index as it has a minimal overlap with the normal population. He has suggested LA/AO greater than 1.17 plus a left atrium greater than 4.2 cm as a criterion for LA enlargement. The present study also had a mean LA/AO ratio 0.95 ± 0.22 (0.73 to 1.17); the upper limit is similar to that reported by Brown et al. [1]

 :: References Top

1.Brown, 0. R., Harrison, D. C. and Popp, R. L.: An improved method for echo­graphic detection of left atrial enlarge­ment. Circulation, 50: 58-64: 1974.  Back to cited text no. 1    
2.Carleton, R. A. and Graettinger, J. S.: The haemodynamic role of atria with or without mitral stenosis. Amer. J. Med., 42: 532-538, 1967.  Back to cited text no. 2    
3.DuBois, E. F.: "Basal metabolism in health and disease". 3rd Edition Lea and Febiger, Philadelphia, 1936.  Back to cited text no. 3    
4.Feigenbaum, H.: "Echocardiography" 2nd Edition. Lea and Febiger. Philadelphia, 1976.  Back to cited text no. 4    
5.Francis, G. S. and Hagan, A. D.: Echo­cardiographic criteria of normal left aerial size in adults. Circulation, (suppl. 111). 50: 76, 1974 (abs).  Back to cited text no. 5    
6.Goldberg, S. J., Allen, H. D., Sahn, D J., Friedman, W. F. and Harris, T.: A prospective 21 year experience with echocardiographic evaluation of prema­tures with patent ductus arteriosus (PDA) and respiratory distress syndrome (RDS). Amer. J. Cardiol., 35: 139, 1975 (abs).  Back to cited text no. 6    
7.Hagan, A. D., Deely, W. J., Sahn, D. J. and Friedman, W. F.: Echocardiographic criteria for the normal newborn infants. Circulation, 48: 1221-1226, 1973.  Back to cited text no. 7    
8.Hirata, T., Wolfe, S. B., Popp, R. L., Helmen, C. H and Feigenbaum, H.: Esti­mation of left atrial size using ultrasound. Amer. Heart J., 78: 43-52, 1969.  Back to cited text no. 8    
9.Schableman, S. E., Schiller, N. B., Anschuetz, R. A., Silverman, N. H. and Glantz, S. A.: Comparison of four two­dimensional echocardiographic views for measuring left atrial size. Amer. J. Cardiol., 41 (abs): 391, 1978.  Back to cited text no. 9    
10.tenCate, F. J., Kloster, F. E., vanDorp, W. G., Meester, G. T. and Roelandt, J.: Dimensions and volumes of left atrium and ventricle determined by single beam echocardiography. Brit. Heart J. 36: 737-746, 1974.  Back to cited text no. 10    


  [Figure 1]

  [Table 1]


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