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| ARTICLE |
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| Year : 1978 | Volume
: 24
| Issue : 4 | Page : 214-217 |
Effect of 0.1% ethacridine lactate on the vas deferens and human spermatozoa- (A preliminary report based on animal and in vitro experiments)
DS Kamat, EK Bharucha
Departments of Obstetrics & Gynecology and Surgery, B.J. Medical College and Sassoon General Hospitals, Poona 1., India
Correspondence Address:
D S Kamat
Departments of Obstetrics & Gynecology and Surgery, B.J. Medical College and Sassoon General Hospitals, Poona 1.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 745149 
Ethacridine Lactate (0.1%) has been tried in dogs to show it's safety by clinical and histopathological examination of vas at different time intervals. Also in vitro titration was carried out with normal human semen and serially diluted ethacridine lactate.
With this preliminary study, 0.1% Ethacridine lactate was found to be safe and effective for flushing the distal vas at the time of vasectomy for producing immediate azoospermia. It was also found to cause instant immobilization and lysis of the spermatozoa.
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