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Year : 1978  |  Volume : 24  |  Issue : 3  |  Page : 158-163

A study of cholesterol/phospholipid ratio and triene/tetraene ratio in coronary heart disease

Department of Biochemistry and Nutrition, Seth G. S. Medical College, Parel, Bombay-400 012, India

Correspondence Address:
K G Tanksale
Department of Biochemistry and Nutrition, Seth G. S. Medical College, Parel, Bombay-400 012
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Source of Support: None, Conflict of Interest: None

PMID: 722612

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The biochemical assessment of coronary heart diseases (CHD) is done by studying serum lipids. This is usually done to under­stand the pathogenesis o f atherosclerosis which is the cause o f CHD. Indoor patients suffering from CHD were studied for their serum cholesterol, phospholipids, total fatty acids and polyunsaturated fatty acids (PUFA). Cholesterol/phospholipid and triene/tetraene ratios were calculated. It was observed that there was no significant difference in any of the parameters studied on the basis of dietary habit or body size. It was further observed on the basis of triene/tetraene ratio that the patients were ingesting adequate amounts of linoleate, there were high levels of cholesterol, phospholipids and c/p ratio in all the groups. This paradox may be due to disturbed PUFA metabolism and particularly of linoleate so that there is no influence o f linoleate on cholesterol and phospholipid synthesis.

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Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow