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| ARTICLE |
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| Year : 1977 | Volume
: 23
| Issue : 3 | Page : 106-111 |
Single versus divided doses of sintamil in depression
DR Doongaji, A Sheth, JS Apte, MR Datt, VK Mundra
Department of Psychiatry, Seth G, S. Medical College and K.E.M. Hospital, Parel, Bombay-400 012, India
Correspondence Address:
D R Doongaji
Department of Psychiatry, Seth G, S. Medical College and K.E.M. Hospital, Parel, Bombay-400 012
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 351176 
Fifty one out-patient depressives were treated with Sintamil for a 5 week trial period under double-blind conditions. Sintamil 75 mg/day was administered in a fixed dosage schedule either as a single daily dose (SDS) or in 3 divided doses (DDS). There were no significant differences between the two treatment modalities in so far as efficacy was concerned. The SDS regimen of drug administration was associated with a lesser incidence of side effects.
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