Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & ISI's SCI  
Users online: 608  
Home | Subscribe | Feedback | Login 
About Latest Articles Back-Issues Articlesmenu-bullet Search Instructions Online Submission Subscribe Etcetera Contact
 :: Next article
 :: Previous article 
 :: Table of Contents
 ::  Similar in PUBMED
 ::  Search Pubmed for
 ::  Search in Google Scholar for
 ::  [PDF Not available] *
 ::  Citation Manager
 ::  Access Statistics
 ::  Reader Comments
 ::  Email Alert *
 ::  Add to My List *
* Registration required (free) 

  IN THIS Article
 ::  Abstract
 ::  Case report
 ::  Comments
 ::  References
 ::  Article Figures

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal


Year : 1977  |  Volume : 23  |  Issue : 2  |  Page : 89-90

Situs inversus totalis with calculus cholecystitis and mucinous cystadenomas of ovaries

Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh-160011, India

Correspondence Address:
P G Rao
Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh-160011
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 614420

Rights and PermissionsRights and Permissions

 :: Abstract 

An uncommon case of cholelithiasis and cholecystitis with mucinous cystadenomas of ovaries in situs inversus totalis is presented along with its clinical implications. Clinical and radio­logical signs in diagnosis of situs inversus totalis are discussed.

How to cite this article:
Rao P G, Katariya R N, Sood S, Rao P. Situs inversus totalis with calculus cholecystitis and mucinous cystadenomas of ovaries. J Postgrad Med 1977;23:89-90

How to cite this URL:
Rao P G, Katariya R N, Sood S, Rao P. Situs inversus totalis with calculus cholecystitis and mucinous cystadenomas of ovaries. J Postgrad Med [serial online] 1977 [cited 2023 Feb 7];23:89-90. Available from:

Situs inversus totalis is a rare congeni­tal condition occurring in 1 in 5,000 to 1 in 10,000 of all births and in this there is mirror image transposition of both abdo­minal and thoracic viscera. It is compa­tible with normal life and any disease process can effect persons with this con­dition. Amoebic liver abscess, [1] chronic duodenal ulcer, [6] acute appendicitis, [5] ade­nocarcinoma of caecum, [9] jejunal and ileal atresia [4] have all been reported with situs inversus totalis. Chronic cholecystitis and cholelithiasis has also been docu­mented. We have been able to trace only 26 cases of cholelithiasis [2],[6],[7],[8],[9] with situs inversus totalis in English literature, and the rarity of this condition has prompted us to report this case.

 :: Case report Top

A 56 year old female patient who was known to have true dextrocardia, pre­sented as an emergency with colicky pain in the left hypochondrium of 18 hours' duration. On examination, she was found to be anicteric, obese lady with normal pulse rate and blood pressure. Abdominal examination showed a globu­lar, 4 x 3 cms. tender mass in the left hypochondrium which was moving with respirations. Cardiovascular system re­vealed the apex beat in the right fifth in­tercostal space with heart sounds best heard on the right side.

A clinical diagnosis of situs inversus totalis with left sided acute cholecystitis was made, which was later confirmed by chest X-ray See [Figure 1] on page 88B, barium meal examination and oral cholecystogram See [Figure 2] on page 88B which revealed a functioning left sided gall bladder with multiple filling defects.

The patient was eventually explored through an upper abdominal midline in­cision. Falciform ligament was found to be going to the left side and there was complete transposition of abdominal viscera. The stomach and spleen were on the right side. Gall bladder was on left side and contained multiple stones. The common bile duct was situated to the left of the midline and was of normal size. Ileocaecal region was in the left iliac fossa and sigmoid colon was in the right iliac fossa. Both ovaries were stud­ed with multiple cysts. Operative cho­langiogram, cholecystectomy, appendicec­tomy and bilateral oophorectomy were carried out. Histological examination showed evidence of chronic colecystitis in the gall bladder, chronic appendicitis in appendix and mutinous cystadenomas of both ovaries. Postoperative period of the patient was uneventful.

 :: Comments Top

In situs inversus totalis, though there is transposition of all viscera, innerva­tion remains the same as in normal per­sons. [2] Therefore, more than half of the cases of acute appendicitis in situs in­versus totalis present with symptoms and signs in right iliac fossa. [2] Unaware­ness of this condition can lead to wrong surgical approach in such cases. From collective review of the symptomatology of 26 cases of cholecystitis with situs in­versus, we found that 60 per cent of cases presented with pain in the left hypo­chondrium, 30 per cent with pain in the epigastrium and 10 per cent with pain in the right hypochondrium. Our case pre­sented with symptoms and signs in the left hypochondrium.

Clinical diagnosis of situs inversus totalis is possible by detecting the apex heat in the right fifth intercostal space with heart sounds better heard on the right of the chest and by detecting liver dullness on the left side. The presence of right testes lower than left in the scrotum has been described as a helpful diagnostic sign in males. [2]

Skiagram of the chest showing right sided heart, plain X-ray of abdomen showing stomach bubble under right dome of diaphragm and liver shadow on the left side, and barium meal and enema provide full proof for the diagnosis of situs inversus totalis.

Oral cholecystography with 10 x 12 inch film and exposure on right side can be misinterpreted as non-functioning gall bladder in situs inversus totalis and, therefore, 14" x 17" film of abdomen has been suggested to overcome this diffi­culty. [8]

 :: References Top

1.Ansari, Z. A., Skaria, J.. Gopal. M. S., Vaish, S. K. and Rai, R. N.: Situs in­versus with Amoebic liver abscess. J. Trop. Med. Hyg. 76: 169-170, 1973.  Back to cited text no. 1    
2.Cholst, M. R.: Discrepencies in pain and symptom destribu'ion. Position of the testicles as a diagnostic sign in situs in­versus totalis. Amer. J. Surg. 73: 104­107, 1947.  Back to cited text no. 2    
3.Etter, L. E.: Left sided gall bladder. Amer J. Roentgenol. 70: 987-990. 1953.  Back to cited text no. 3    
4.Fonkalsrud, E. W., Tompkins, R. and Clotworthy, W.: Abdominal manifesta­tions of situs inversus in infants and children. Arch. Surg, 92: 791-795, 1966.  Back to cited text no. 4    
5.Helgerson, L. O., Kuehner, C. R. and Stanley-Brown, E. G.: Acute appendicitis in a child with complete situs inversus. J. Paediat. Surg. 5: 379-380, 1970.  Back to cited text no. 5    
6.Mayo, C. W. and Rice, R. G.: Situs in­versus totalis. Statistical review of data on 76 cases with special reference to diseases of the biliary tract. Arch. Surg. 58: 724-730, 1949.  Back to cited text no. 6    
7.Southam, J. A.: Lefi sided gall bladder. Calculous cholecystitis with situs in­versus. Ann. Surg. 182: 135-137, 1975.  Back to cited text no. 7    
8.Wood, G. and Blalock, A.: Situs inversus totalis and diseases of the biliary tract. Arch. Surg. 40: 885-896, 1940.  Back to cited text no. 8    
9.Wright, C. B. and Morton, C. B.: Situs inversus totalis with adenocarcinoma of caecum. American Surgeon. 37: 65-66, 1971.  Back to cited text no. 9    


  [Figure 1], [Figure 2]


Print this article  Email this article
Previous article Next article
Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow