|
| ARTICLE |
|
| Year : 1976 | Volume
: 22
| Issue : 4 | Page : 171-175 |
In vitro susceptibility of urinary pothogens to trimethoprim, nitrofurantoin and trimethoprim-nitrofurantoin combination
Pervin Anklesaria1, Swati Paranjpe1, Kusum Gupta1, Vidya Acharya1, Teresa Paul1, UK Sheth2
1 Department of Pharmacology, Clinical Drug trial Unit, Council of Scientific and Industrial Research (CSIR) and The Department of Medicine, Seth G. S. Medical College, Parel, Bombay-400012., India
2 Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400012, India
Correspondence Address:
Pervin Anklesaria
Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400012.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 802242 
Trimethoprim and Nitrofurantoin are both effective against urinary tract infections. Trimethoprim till now has been used in combination with sulphamethoxazole. We have investigated the combination of Trimethoprim and Nitrofurantoin on 182 pathogenic cultures isolated from 165 cases of urinary tract infection which had a significant colony count of >10 5 orgs/ml. 65% of the strains exhibited synergy to the combination. Clinical results of this combination are very promising and are reported in another communication.
[FULL TEXT] [PDF Not available]*
|
