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Year : 1976  |  Volume : 22  |  Issue : 4  |  Page : 171-175

In vitro susceptibility of urinary pothogens to trimetho計rim, nitrofurantoin and trimethoprim-nitrofurantoin combination

1 Department of Pharmacology, Clinical Drug trial Unit, Council of Scientific and Industrial Research (CSIR) and The Department of Medicine, Seth G. S. Medical College, Parel, Bombay-400012., India
2 Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400012, India

Correspondence Address:
Pervin Anklesaria
Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400012.
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Source of Support: None, Conflict of Interest: None

PMID: 802242

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Trimethoprim and Nitrofurantoin are both effective against urinary tract infections. Trimethoprim till now has been used in combination with sulphamethoxazole. We have investigated the combination of Trimethoprim and Nitrofurantoin on 182 pathogenic cultures isolated from 165 cases of urinary tract infection which had a significant colony count of >10 5 orgs/ml. 65% of the strains exhibited synergy to the combination. Clinical results of this combi要ation are very promising and are reported in another communica負ion.

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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow